Management of nonalcoholic steatohepatitis. An evidence-based approach

Suzanne E. Mahady, Jacob George

Research output: Contribution to journalReview ArticleResearchpeer-review

41 Citations (Scopus)

Abstract

Nonalcoholic fatty liver disease (NAFLD) and its progressive form, nonalcoholic steatohepatitis (NASH), are an increasingly common cause of chronic liver disease in the developed world, with NASH projected to be the leading cause of liver transplantation in the United States by 2020. This review of NASH management addresses current data from the perspective of levels of evidence for therapeutic options in NASH, including lifestyle modification, drug therapies, and bariatric surgery. In particular, behavioral therapies to assist patients in adopting lifestyle changes are highlighted and a research agenda for future NASH management is presented.

Original languageEnglish
Pages (from-to)631-645
Number of pages15
JournalClinics in Liver Disease
Volume16
Issue number3
DOIs
Publication statusPublished - 1 Aug 2012
Externally publishedYes

Keywords

  • Diet
  • Exercise
  • Fatty liver
  • Nonalcoholic steatohepatitis
  • Therapy

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