Management of dyslipidemia in patients with diabetes

Yu Kataoka, Kiyoko Uno, Stephen J. Nicholls

Research output: Contribution to journalArticleResearchpeer-review

Abstract

Cardiovascular disease is the leading cause of major morbidity and mortality in patients with type 2 diabetes. The recent focus on the apparent lack of cardiovascular benefit associated with glucose-lowering strategies has overshadowed the importance of targeting dyslipidemia for cardiovascular prevention in patients with diabetes. While lowering low-density lipoprotein (LDL) cholesterol is beneficial, diabetes is also characterized by hypertriglyceridemia, low levels of high-density lipoproteHDL-cholesterol and abundant levels of small, dense LDL particles. Accordingly, these factors represent additional targets for therapeutic modification in order to achieve more effective reductions in cardiovascular risk.

Original languageEnglish
Pages (from-to)40-45
Number of pages6
JournalUS Endocrinology
Volume7
Issue number1
DOIs
Publication statusPublished - 1 Aug 2011
Externally publishedYes

Keywords

  • Diabetes mellitus
  • Diabetic dyslipidemia
  • Hypertriglyceridemia
  • Insulin resistance
  • LDL-cholesterol-lowering therapy
  • Low HDL-cholesterol
  • Statin

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