Management of cholesterol to reduce the burden of stroke in Asia: Consensus statement

Graeme John Hankey, Ka S.L. Wong, Siwaporn Chankrachang, Christopher Chen, Denis Crimmins, Judith Frayne, Jong Su Kim, Yansheng Li, Chia Wei Liou, Julia S. Merican, Jusuf Misbach, Hector Jose Navarro, Yukito Shinohara, Yongjun Wang, Byung-Woo Yoon

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13 Citations (Scopus)

Abstract

Stroke is a major cause of morbidity and mortality in Asia, and its pattern is changing. The incidence of haemorrhagic stroke is declining while the incidence of ischaemic stroke caused by large artery atherothromboembolism is increasing secondary to an increase in the prevalence of hypercholesterolaemia. The Working Group on Stroke and Lipids Management in Asia Consensus Panel assembled leading experts from the region to reach a consensus on how to address this challenge. The group discussed the observational epidemiology of the relationship between cholesterol and risk of stroke, the clinical trial evidence base for cholesterol-lowering for stroke prevention, and issues specific to stroke and lipid management for Asian doctors and patients. Stroke guidelines from many of the Asian countries have recently recommended consideration of statins for recurrent stroke prevention in patients with previous ischaemic stroke or transient ischaemic attack. However, because these recommendations have yet to be implemented widely, there is a need to educate Asian physicians and patients about the importance of adequate control of hypercholesterolaemia. Further trials of statins in Asian patients are also needed, particularly in those with intracranial stenosis.

Original languageEnglish
Pages (from-to)209-216
Number of pages8
JournalInternational Journal of Stroke
Volume5
Issue number3
DOIs
Publication statusPublished - Jun 2010
Externally publishedYes

Keywords

  • Asia
  • Lipids
  • Prevention
  • Risk factors
  • Statins
  • Stroke

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