TY - JOUR
T1 - Malaysia’s breakthrough in modern actinobacteria (MOD-ACTINO) drug discovery research
AU - Thye, Angel Yun-Kuan
AU - Letchumanan, Vengadesh
AU - Tan, Loh Teng-Hern
AU - Law, Jodi Woan-Fei
AU - Lee, Learn-Han
N1 - Funding Information:
Funding: This research was funded by Ministry of (FRGS/1/2019/SKK08/MUSM/02/7), awarded to L-HL.
Funding Information:
This research was funded by Ministry of Education—Fundamental Research Grant Scheme (FRGS/1/2019/SKK08/MUSM/02/7), awarded to L-HL.
Publisher Copyright:
© 2022, HH Publisher. All rights reserved.
PY - 2022/1/20
Y1 - 2022/1/20
N2 - Actinobacteria are well-known producers of metabolites with medicinal value. The application of actinobacterial compounds has been expanded to other fields, including agriculture, aquaculture, and cosmeceutical. With this, the term “Modern Actinobacteria” (MOD-ACTINO) was first coined by a Malaysian researcher, Associate Professor Dr. Lee Learn Han, to define actinobacteria with modern applications. The present review aims to highlight the MOD-ACTINO research achievements in Malaysia. The Malaysian MOD-ACTINO strains are capable of exerting a wide range of bioactivities such as antimicrobial/anti-MRSA, anticancer, antioxidant, antifungal, and antimalarial. Research on MOD-ACTINO is highly encouraged to harness the benefits of actinobacteria and unravel important metabolites for various applications.
AB - Actinobacteria are well-known producers of metabolites with medicinal value. The application of actinobacterial compounds has been expanded to other fields, including agriculture, aquaculture, and cosmeceutical. With this, the term “Modern Actinobacteria” (MOD-ACTINO) was first coined by a Malaysian researcher, Associate Professor Dr. Lee Learn Han, to define actinobacteria with modern applications. The present review aims to highlight the MOD-ACTINO research achievements in Malaysia. The Malaysian MOD-ACTINO strains are capable of exerting a wide range of bioactivities such as antimicrobial/anti-MRSA, anticancer, antioxidant, antifungal, and antimalarial. Research on MOD-ACTINO is highly encouraged to harness the benefits of actinobacteria and unravel important metabolites for various applications.
KW - Actinomycetes
KW - Anticancer
KW - Antimicrobial
KW - Antioxidant
KW - Drug discovery
KW - Modern actinobacteria
KW - Streptomycetes
UR - http://www.scopus.com/inward/record.url?scp=85146382730&partnerID=8YFLogxK
U2 - 10.36877/pmmb.a0000275
DO - 10.36877/pmmb.a0000275
M3 - Review Article
AN - SCOPUS:85146382730
SN - 2637-1049
VL - 5
JO - Progress in Microbes and Molecular Biology
JF - Progress in Microbes and Molecular Biology
IS - 1
M1 - a0000275
ER -