TY - JOUR
T1 - Malaria Parasites in a Hungry Host
T2 - Kinases and Host Caloric Restriction Brought Together
AU - Garcia-Bustos, Jose F.
AU - Doerig, Christian
PY - 2017/11
Y1 - 2017/11
N2 - A study recently published in Nature links reduced calorie nutritional intake of host mice with (i) reduced severity of cerebral malaria, (ii) decreased parasitemia, and (iii) activation of a nutrient-sensing pathway that regulates the parasite's proliferation rate. Here, we discuss these findings in the context of human malaria pathology and Plasmodium kinomics.
AB - A study recently published in Nature links reduced calorie nutritional intake of host mice with (i) reduced severity of cerebral malaria, (ii) decreased parasitemia, and (iii) activation of a nutrient-sensing pathway that regulates the parasite's proliferation rate. Here, we discuss these findings in the context of human malaria pathology and Plasmodium kinomics.
UR - http://www.scopus.com/inward/record.url?scp=85028856394&partnerID=8YFLogxK
U2 - 10.1016/j.pt.2017.08.007
DO - 10.1016/j.pt.2017.08.007
M3 - Article
AN - SCOPUS:85028856394
VL - 33
SP - 831
EP - 832
JO - Trends in Parasitology
JF - Trends in Parasitology
SN - 1471-4922
IS - 11
ER -