MTI has the potential to detect abnormalities in normal-appearing white and gray matter on conventional MR imaging. Early detection methods and disease progression markers are needed in HD research. Therefore, we investigated MTI parameters and their clinical correlates in premanifest and manifest HD.
van den Bogaard, S. J. A., Dumas, E. M., Milles, J., Reilmann, R., Stout, J. C., Craufurd, D. O., van Buchem, M. A., van der Grond, J., & Roos, R. A. C. (2012). Magnetization transfer imaging in premanifest and manifest Huntington disease. American Journal of Neuroradiology, 33(5), 884 - 889. https://doi.org/10.3174/ajnr.A2868