Magnetic resonance spectroscopy of the brain: review of metabolites and clinical applications

D. P. Soares, M. Law

Research output: Contribution to journalReview ArticleResearchpeer-review

283 Citations (Scopus)

Abstract

Magnetic resonance imaging (MRI) provides anatomic images and morphometric characterization of disease, whereas magnetic resonance spectroscopy (MRS) provides metabolite/biochemical information about tissues non-invasively in vivo. MRS has been used clinically for more than two decades. The major applications of this advanced MRI tool are in the investigation of neurological and neurosurgical disorders. MRS has also been used in the evaluation of the prostate gland and muscle tissue, but these applications will not be addressed in this review. The aim of this review is to attempt to introduce the technique, review the metabolites and literature, as well as briefly describe our clinical experience.

Original languageEnglish
Pages (from-to)12-21
Number of pages10
JournalClinical Radiology
Volume64
Issue number1
DOIs
Publication statusPublished - 1 Jan 2009
Externally publishedYes

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