Macrophage accumulation at a site of renal inflammation is dependent on the M-CSF/c-fms pathway

Yannick Le Meur, Gregory H Tesch, Prudence A Hill, Wei Mu, R Foti, David J Nikolic-Paterson, Robert Atkins

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69 Citations (Scopus)

Abstract

Production of macrophage-colony stimulating factor (M-CSF), the major macrophage growth factor, is increased in tissues during inflammation. Therefore, we determined whether M-CSF, acting through its receptor c-fms, contributes to macrophage accumulation at a site of tissue injury.
Original languageEnglish
Pages (from-to)530 - 537
Number of pages8
JournalJournal of leukocyte biology
Volume72
Issue number3
Publication statusPublished - 2002

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