Machine-learning-scheme to detect Choroidal-Neovascularization in retinal OCT image

Venkatesan Rajinikanth, Seifedine Kadry, Robertas Damasevicius, David Taniar, Hafiz Tayyab Rauf

Research output: Chapter in Book/Report/Conference proceedingConference PaperResearchpeer-review

19 Citations (Scopus)


Eye is a fundamental sensory organ and any disease in eye will severely affect the sensory signal evaluation and conclusion making capability of the brain. The Choroidal-Neovascularization (CNV) is one of the harsh eye diseases in which a new blood-vessel grow from the choroid. Usually, the major cause of CNV is due to wet Age-Related-Macular-Degeneration (ARMD) and the formed new vessel will cause a leak in fluid which makes the retinal wet. The untreated CNV will lead to vision loss. In this research, detection of CNV using Optical-Coherence-Tomography (OCT) is presented using 484 images (242 Healthy and 242 CNV). In this work, a Machine-Learning-Scheme (MLS) is developed to examine the resized OCT of 256x256 pixels and the stages of this MLS includes; pre-processing, feature extraction, Mayfly-Optimization-Algorithm (MFA) based feature reduction, and two-class classification. The experimental outcome of this technique confirmed that the Fine-Gaussian-SVM (SVM-FG) classifier helped to accomplish an improved classification accuracy (>92%) compared to the alternative classifiers of this study.

Original languageEnglish
Title of host publicationProceedings of 2021 IEEE Seventh International Conference on Bio Signals, Images and Instrumentation
Place of PublicationPiscataway NJ USA
PublisherIEEE, Institute of Electrical and Electronics Engineers
Number of pages5
ISBN (Electronic)9781665441261
ISBN (Print)9781665431002
Publication statusPublished - 2021
EventIEEE International Conference on Bio Signals, Images and Instrumentation 2021 - Chennai, India
Duration: 25 Mar 202127 Mar 2021
Conference number: 7th (Proceedings)


ConferenceIEEE International Conference on Bio Signals, Images and Instrumentation 2021
Abbreviated titleICBSII 2021
Internet address


  • Choroidal-Neovascularization
  • Classification
  • Mayfly-Optimization-Algorithm
  • OCT image
  • Retinal OCT

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