Machine learning for sperm selection

Jae Bem You, Christopher McCallum, Yihe Wang, Jason Riordon, Reza Nosrati, David Sinton

Research output: Contribution to journalReview ArticleResearchpeer-review

42 Citations (Scopus)

Abstract

Infertility rates and the number of couples seeking fertility care have increased worldwide over the past few decades. Over 2.5 million cycles of assisted reproductive technologies are being performed globally every year, but the success rate has remained at ~33%. Machine learning, an automated method of data analysis based on patterns and inference, is increasingly being deployed within the health-care sector to improve diagnostics and therapeutics. This technique is already aiding embryo selection in some fertility clinics, and has also been applied in research laboratories to improve sperm analysis and selection. Tremendous opportunities exist for machine learning to advance male fertility treatments. The fundamental challenge of sperm selection — selecting the most promising candidate from 108 gametes — presents a challenge that is uniquely well-suited to the high-throughput capabilities of machine learning algorithms paired with modern data processing capabilities.

Original languageEnglish
Pages (from-to)387–403
Number of pages17
JournalNature Reviews Urology
Volume18
DOIs
Publication statusPublished - 17 May 2021

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