TY - JOUR
T1 - Machine learning for sperm selection
AU - You, Jae Bem
AU - McCallum, Christopher
AU - Wang, Yihe
AU - Riordon, Jason
AU - Nosrati, Reza
AU - Sinton, David
N1 - Funding Information:
This work was supported by the Collaborative Health Research Project funded by the Canadian Institute of Health Research (CIHR) and the Natural Sciences and Engineering Research Council of Canada (NSERC). R.N. acknowledges support from the Australian Research Council Discovery Program (DP190100343). The authors also gratefully acknowledge the Canada Research Chairs Program (DS). The authors thank K. Jarvi, T. Hannam and A. Lagunov for insightful discussions on the potential for machine learning in clinical applications.
Publisher Copyright:
© 2021, Springer Nature Limited.
Copyright:
Copyright 2021 Elsevier B.V., All rights reserved.
PY - 2021/5/17
Y1 - 2021/5/17
N2 - Infertility rates and the number of couples seeking fertility care have increased worldwide over the past few decades. Over 2.5 million cycles of assisted reproductive technologies are being performed globally every year, but the success rate has remained at ~33%. Machine learning, an automated method of data analysis based on patterns and inference, is increasingly being deployed within the health-care sector to improve diagnostics and therapeutics. This technique is already aiding embryo selection in some fertility clinics, and has also been applied in research laboratories to improve sperm analysis and selection. Tremendous opportunities exist for machine learning to advance male fertility treatments. The fundamental challenge of sperm selection — selecting the most promising candidate from 108 gametes — presents a challenge that is uniquely well-suited to the high-throughput capabilities of machine learning algorithms paired with modern data processing capabilities.
AB - Infertility rates and the number of couples seeking fertility care have increased worldwide over the past few decades. Over 2.5 million cycles of assisted reproductive technologies are being performed globally every year, but the success rate has remained at ~33%. Machine learning, an automated method of data analysis based on patterns and inference, is increasingly being deployed within the health-care sector to improve diagnostics and therapeutics. This technique is already aiding embryo selection in some fertility clinics, and has also been applied in research laboratories to improve sperm analysis and selection. Tremendous opportunities exist for machine learning to advance male fertility treatments. The fundamental challenge of sperm selection — selecting the most promising candidate from 108 gametes — presents a challenge that is uniquely well-suited to the high-throughput capabilities of machine learning algorithms paired with modern data processing capabilities.
UR - http://www.scopus.com/inward/record.url?scp=85108831393&partnerID=8YFLogxK
U2 - 10.1038/s41585-021-00465-1
DO - 10.1038/s41585-021-00465-1
M3 - Review Article
C2 - 34002070
AN - SCOPUS:85108831393
SN - 1759-4812
VL - 18
SP - 387
EP - 403
JO - Nature Reviews Urology
JF - Nature Reviews Urology
ER -