Low relative abundances of the mucolytic bacterium Akkermansia muciniphila and Bifidobacterium spp. in feces of children with autism

Lv Wang, Claus T. Christophersen, Michael J. Sorich, Jacobus P. Gerber, Manya T. Angley, Michael A. Conlon

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184 Citations (Scopus)


Gastrointestinal disturbance is frequently reported for individuals with autism. We used quantitative real-time PCR analysis to quantify fecal bacteria that could influence gastrointestinal health in children with and without autism. Lower relative abundances of Bifidobacteria species and the mucolytic bacterium Akkermansia muciniphila were found in children with autism, the latter suggesting mucus barrier changes.

Original languageEnglish
Pages (from-to)6718-6721
Number of pages4
JournalApplied and Environmental Microbiology
Issue number18
Publication statusPublished - Sep 2011
Externally publishedYes

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