Low frequency maintenance ganciclovir for cytomegalovirus retinitis

Anthony J.H. Hall; Hector Maclean; Ian D. Jennens; C. Ron Lucas; A. Murray Sandland

doi:10.3109/00365549109023373

Low frequency maintenance ganciclovir for cytomegalovirus retinitis

Anthony J.H. Hall, Hector Maclean, Ian D. Jennens, C. Ron Lucas, A. Murray Sandland

Research output: Contribution to journal › Article › Research › peer-review

10 Citations (Scopus)

Abstract

45 patients on maintenance ganciclovir for treated cytomegalovirus (CMV) retinitis were reviewed retrospectively. Treatment was given at 30 mg/kg/week in 3 divided doses: Monday, Wednesday, Friday. The median time to clinical relapse was 5.4 months. This is similar to that reported with higher frequency maintenance regimens. The high degree of immunodeficiency (median CD4 count 16 cells/μl) and poor prognosis (median survival 8.2 months) associated with CMV retinitis were confirmed.

Original language	English
Pages (from-to)	43-46
Number of pages	4
Journal	Scandinavian Journal of Infectious Diseases
Volume	23
Issue number	1
DOIs	https://doi.org/10.3109/00365549109023373
Publication status	Published - 1991
Externally published	Yes

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title = "Low frequency maintenance ganciclovir for cytomegalovirus retinitis",

abstract = "45 patients on maintenance ganciclovir for treated cytomegalovirus (CMV) retinitis were reviewed retrospectively. Treatment was given at 30 mg/kg/week in 3 divided doses: Monday, Wednesday, Friday. The median time to clinical relapse was 5.4 months. This is similar to that reported with higher frequency maintenance regimens. The high degree of immunodeficiency (median CD4 count 16 cells/μl) and poor prognosis (median survival 8.2 months) associated with CMV retinitis were confirmed.",

author = "Hall, {Anthony J.H.} and Hector Maclean and Jennens, {Ian D.} and Lucas, {C. Ron} and Sandland, {A. Murray}",

note = "Funding Information: * AH is in receipt of a research scholarship from the Commonwealth AIDS Research Grants Committee (File No. 90/01555).",

year = "1991",

doi = "10.3109/00365549109023373",

language = "English",

volume = "23",

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T1 - Low frequency maintenance ganciclovir for cytomegalovirus retinitis

AU - Hall, Anthony J.H.

AU - Maclean, Hector

AU - Jennens, Ian D.

AU - Lucas, C. Ron

AU - Sandland, A. Murray

N1 - Funding Information: * AH is in receipt of a research scholarship from the Commonwealth AIDS Research Grants Committee (File No. 90/01555).

PY - 1991

Y1 - 1991

N2 - 45 patients on maintenance ganciclovir for treated cytomegalovirus (CMV) retinitis were reviewed retrospectively. Treatment was given at 30 mg/kg/week in 3 divided doses: Monday, Wednesday, Friday. The median time to clinical relapse was 5.4 months. This is similar to that reported with higher frequency maintenance regimens. The high degree of immunodeficiency (median CD4 count 16 cells/μl) and poor prognosis (median survival 8.2 months) associated with CMV retinitis were confirmed.

AB - 45 patients on maintenance ganciclovir for treated cytomegalovirus (CMV) retinitis were reviewed retrospectively. Treatment was given at 30 mg/kg/week in 3 divided doses: Monday, Wednesday, Friday. The median time to clinical relapse was 5.4 months. This is similar to that reported with higher frequency maintenance regimens. The high degree of immunodeficiency (median CD4 count 16 cells/μl) and poor prognosis (median survival 8.2 months) associated with CMV retinitis were confirmed.

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DO - 10.3109/00365549109023373

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VL - 23

SP - 43

EP - 46

JO - Scandinavian Journal of Infectious Diseases

JF - Scandinavian Journal of Infectious Diseases

IS - 1

ER -

Low frequency maintenance ganciclovir for cytomegalovirus retinitis

Abstract

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