Longitudinal Modulation Studies for Augmentation of Injection and Detection in Capillary Gas Chromatography

Russell M. Kinghorn, Philip J. Marriott, Peter A. Dawes

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18 Citations (Scopus)

Abstract

A longitudinally modulated cryogenic system (LMCS) was used for detection and injection enhancement in capillary gas chromatography. Several modes of operation were evaluated, including discrete and continuous modulation. This later operating mode was also used to study column bleed profiles obtained over a wide temperature program range. It was found that the trapped-then-remobilized bleed profile matches closely to that seen in normal gas chromatography, except that the concentrated pulses of bleed constituents have a greatly increased response. In addition, this procedure appears to have potential for understanding the molecular make-up of column bleed. The LMCS was also evaluated as a reinjection device in capillary gas chromatography. Increases in efficiencies of up to 210% arising from reduced peak widths were observed under some operating conditions, thus offering a mechanism for routine narrow injection bandwidths in capillary chromatography.

Original languageEnglish
Pages (from-to)611-616
Number of pages6
JournalJournal of Microcolumn Separations
Volume10
Issue number7
DOIs
Publication statusPublished - 1 Jan 1998
Externally publishedYes

Keywords

  • Capillary gas chromatography
  • Column bleed
  • Cryogenic trapping
  • Detection enhancement
  • Longitudinal modulation

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