Longitudinal Cognitive Decline in Patients With Mild Cognitive Impairment or Dementia Due to Alzheimer’s Disease

Yen Ying Lim, Jessica Kong, P. Maruff, J. Jaeger, Ellen Huang, Elena Ratti

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)

Abstract

Sensitive cognitive assessments accurately detect and track cognitive decline in Alzheimer’s disease. The Cogstate battery was used to measure cognitive change in cognitively normal participants and in individuals with mild cognitive impairment and mild Alzheimer’s disease enrolled in the Australian Imaging, Biomarker and Lifestyle Rate of Change Substudy. Over 18 months, verbal episodic memory performance declined for mild cognitive impairment and mild Alzeheimer’s disease groups when compared to cognitively normal participants. Frequent assessments of episodic memory may facilitate early detection of cognitive decline due to Alzheimer’s disease.

Original languageEnglish
Pages (from-to)178-183
Number of pages6
JournalJournal of Prevention of Alzheimer's Disease
Volume9
Issue number1
DOIs
Publication statusPublished - Jan 2022

Keywords

  • Alzheimer’s disease
  • cognitive decline
  • Cogstate Brief Battery
  • International Shopping List Test
  • mild cognitive impairment

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