Long distance bicycle riding causes prostate-specific antigen to increase in men aged 50 years and over

Sandra L Mejak, Julianne Bayliss, Shayne D Hanks

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18 Citations (Scopus)


To investigate whether bicycle riding alters total prostate-specific antigen (tPSA) serum concentrations in healthy older men. Methods: 129 male participants, ranging in age from 50 to 71 years (mean 55 years), rode in a recreational group bicycle ride of between 55 and 160 kilometers. Blood samples for tPSA analysis were drawn within 60 minutes before starting, and within 5 minutes after completing the ride. The pre-cycling and post-cycling tPSA values were log transformed for normality and compared using paired t-tests. Linear regression was used to assess the relationship between changes in tPSA with age and distance cycled. Results: Bicycle riding caused tPSA to increase by an average of 9.5 (95 CI = 6.1-12.9; p
Original languageEnglish
Article numbere56030
Number of pages6
JournalPLoS ONE
Issue number2
Publication statusPublished - 2013

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