TY - JOUR
T1 - Locally extensive angio-invasive Scedosporium prolificans infection following resection for squamous cell lung carcinoma
AU - Holmes, Natasha
AU - Trevillyan, Janine Maree
AU - Kidd, Sarah Elizabeth
AU - Leong, Trishe
PY - 2013
Y1 - 2013
N2 - We report a case of Scedosporium prolificans infection in a patient following surgery for squamous cell lung carcinoma. Combination therapy with voriconazole and terbinafine was commenced for intrathoracic infection and mycotic vasculitis. In spite of antifungal treatment, he developed culture-positive sternal and rib osteomyelitis four months later. Scedosporiosis is not commonly reported in patients with solid organ malignancies, and this case highlights its aggressive nature and propensity for direct local invasion.
AB - We report a case of Scedosporium prolificans infection in a patient following surgery for squamous cell lung carcinoma. Combination therapy with voriconazole and terbinafine was commenced for intrathoracic infection and mycotic vasculitis. In spite of antifungal treatment, he developed culture-positive sternal and rib osteomyelitis four months later. Scedosporiosis is not commonly reported in patients with solid organ malignancies, and this case highlights its aggressive nature and propensity for direct local invasion.
UR - http://www.sciencedirect.com/science/article/pii/S2211753913000195
U2 - 10.1016/j.mmcr.2013.04.001
DO - 10.1016/j.mmcr.2013.04.001
M3 - Article
VL - 2
SP - 98
EP - 102
JO - Medical Mycology Case Reports
JF - Medical Mycology Case Reports
SN - 2211-7539
IS - 1
ER -