Locally extensive angio-invasive Scedosporium prolificans infection following resection for squamous cell lung carcinoma

Natasha Holmes, Janine Maree Trevillyan, Sarah Elizabeth Kidd, Trishe Leong

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13 Citations (Scopus)


We report a case of Scedosporium prolificans infection in a patient following surgery for squamous cell lung carcinoma. Combination therapy with voriconazole and terbinafine was commenced for intrathoracic infection and mycotic vasculitis. In spite of antifungal treatment, he developed culture-positive sternal and rib osteomyelitis four months later. Scedosporiosis is not commonly reported in patients with solid organ malignancies, and this case highlights its aggressive nature and propensity for direct local invasion.
Original languageEnglish
Pages (from-to)98 - 102
Number of pages5
JournalMedical Mycology Case Reports
Issue number1
Publication statusPublished - 2013

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