Localization, correlation, and visualization of electroencephalographic surface electrodes and brain anatomy in epilepsy studies

Benjamin H. Brinkmann, Terence J. O'Brien, Richard A. Robb, Frank W. Sharbrough

Research output: Chapter in Book/Report/Conference proceedingConference PaperResearchpeer-review


Advances in neuroimaging have enhanced the clinician's ability to localize the epileptogenic zone in focal epilepsy, but 20-50 percent of these cases still remain unlocalized. Many sophisticated modalities have been used to study epilepsy, but scalp electrode recorded electroencephalography is particularly useful due to its noninvasive nature and excellent temporal resolution. This study is aimed at specific locations of scalp electrode EEG information for correlation with anatomical structures in the brain. 3D position localizing devices commonly used in virtual reality systems are used to digitize the coordinates of scalp electrodes in a standard clinical configuration. The electrode coordinates are registered with a high- resolution MRI dataset using a robust surface matching algorithm. Volume rendering can then be used to visualize the electrodes and electrode potentials interpolated over the scalp. The accuracy of the coordinate registration is assessed quantitatively with a realistic head phantom.

Original languageEnglish
Title of host publicationProceedings of SPIE - The International Society for Optical Engineering
Number of pages11
ISBN (Print)0819424447
Publication statusPublished - 1 Dec 1997
Externally publishedYes
EventConference on Medical Imaging - Physiology and Function from Multidimensional Images 1997 - Newport Beach, United States of America
Duration: 23 Feb 199725 Feb 1997
https://spie.org/Publications/Proceedings/Volume/3033 (Proceedings)


ConferenceConference on Medical Imaging - Physiology and Function from Multidimensional Images 1997
Country/TerritoryUnited States of America
CityNewport Beach
Internet address

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