Local field potential phase modulates neural responses to intracortical electrical stimulation

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4 Citations (Scopus)

Abstract

Cortical visual prostheses could one day help restore sight to the blind by targeting the visual cortex with electrical stimulation. However, power consumption and limited spatial resolution impose limits on performance, while large amounts of electrical charge sometimes necessary to evoke phosphenes can cause seizures. Here, we propose the use of the local field potential as a control signal for the timing of stimulation to reduce charge requirements. In Sprague-Dawley rats, visual cortex was electrically stimulated at random times, and neural responses recorded. Electrical stimulation at specific phases of the local field potential required smaller amounts of charge to elicit spikes than naïve stimulation. Incorporating this into prosthesis design could improve their safety and efficacy.

Original languageEnglish
Title of host publication2020 42nd Annual International Conferences of the IEEE Engineering in Medicine and Biology Society (EMBC)
Place of PublicationPiscataway NJ USA
PublisherIEEE, Institute of Electrical and Electronics Engineers
Pages3521-3524
Number of pages4
ISBN (Electronic)9781728119908
ISBN (Print)9781728119915
DOIs
Publication statusPublished - 2020
EventInternational Conference of the IEEE Engineering in Medicine and Biology Society 2020 - Montreal, Canada
Duration: 20 Jul 202024 Jul 2020
Conference number: 42nd
https://embc.embs.org/2020/
https://ieeexplore.ieee.org/xpl/conhome/9167168/proceeding (Proceedings)

Publication series

NameProceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
PublisherIEEE, Institute of Electrical and Electronics Engineers
Volume2020-July
ISSN (Print)1557-170X
ISSN (Electronic)2694-0604

Conference

ConferenceInternational Conference of the IEEE Engineering in Medicine and Biology Society 2020
Abbreviated titleEMBC 2020
Country/TerritoryCanada
CityMontreal
Period20/07/2024/07/20
Internet address

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