The preparation and characterisation of a new class of reducing agents, lithium alkyl(hydro)dipinan-3α-ylborates, is described. These reagents have been used to reduce a series of ketones (of the type RCOR′) to optically active alcohols with optical yields in the range 5-45%. The stereochemistry of reduction of a series of substituted cyclohexanones is discussed.
|Number of pages||3|
|Journal||Journal of the Chemical Society C: Organic Chemistry|
|Publication status||Published - 1 Dec 1971|