Liquid Chromatography with Electrochemical and/or Spectrophotometric Detection for Automated Determination of Lead, Cadmium, Mercury, Cobalt, Nickel, and Copper

A. M. Bond, G. G. Wallace

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Abstract

In situ formation of dithlocarbamate complexes within a chromatographic system has been Investigated as a method for the simultaneous and automated determination of lead, cadmium, mercury, cobalt, nickel, and copper. The automated, microprocessor-based system developed for the multielement determination can be operated continuously for periods of several days with either spectrophotometric or electrochemical detection. Limits of detection of 1 ng per 10 ¨L. Injected were achieved with spectrophotometric detection. Addition of an Ion exchange based suppressor column to remove excess dithlocarbamate ligand prior to detection Improved spectrophotometric detection limits for nickel, copper, cobalt, and mercury but Is deleterious for determination of lead and cadmium and decreases the period of time over which the automated Instrumentation can be run unattended. Electrochemical detection over extended periods of time employing oxidation at a glassy carbon electrode Is considerably more sensitive for nickel and copper than for the other elements.

Original languageEnglish
Pages (from-to)2085-2090
Number of pages6
JournalAnalytical Chemistry
Volume56
Issue number12
DOIs
Publication statusPublished - Oct 1984
Externally publishedYes

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