Liposomes: an overview of manufacturing techniques

Mohammad Reza Mozafari

Research output: Contribution to journalArticleResearchpeer-review

263 Citations (Scopus)

Abstract

During the last few decades liposomes have attracted great interest as ideal models for biological membranes as well as efficient carriers for drugs, diagnostics, vaccines, nutrients and other bioactive agents. The extensive and ever increasing literature covering the field of liposomology written by researchers with diverse backgrounds is an indication of increasing interest in this field. Many techniques and methodologies have evolved for the manufacture of liposomes, on small and large scales, since their introduction to the scientific community around 40 years ago. This article intends to provide an overview of the advantages and disadvantages of liposome preparation methods in general with particular emphasis on the heating method, developed in our laboratory, as a model technique for fast production of the lipid vesicles.
Original languageEnglish
Pages (from-to)711 - 719
Number of pages9
JournalCellular & Molecular Biology Letters
Volume10
Issue number4
Publication statusPublished - 2005

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