Abstract
Background
Chronic wounds are a silent epidemic. Adequate nutrition is essential to optimise nutritional status, glycaemic control, inflammatory and cardiovascular markers, and subsequently wound healing. The aim of this systematic review is to describe dietary interventions impact on nutritional status, and inflammatory and lipid markers in those living with diabetes and chronic wounds.
Methods
Using PRISMA to guide the review, five databases were searched for intervention studies: Medline, Embase, CINAHL, Scopus, Cochrane Library, and clinical trials registries. The Rob-2 and ROBINS tools assessed risk of bias. Inclusion criteria included nutrition intervention studies in people with chronic wounds and diabetes, and reporting of nutritional status, and inflammatory and lipid markers. Results are synthesised narratively.
Results
Out of 10452 texts, twenty-one studies met inclusion criteria. Sixteen were randomised controlled trials and five were non-randomised. Nineteen studies focused on nutrient supplementation alone, one explored nutrient supplementation combined with nutrition education, and one utilised a multidisciplinary team. Approximately half of studies reported inflammatory markers, lipid and nutrient markers. Lipid and inflammatory markers illustrated mixed results, with only one trial noting significance between groups for all inflammatory markers investigated. Seven out of eight studies reported significant improvements in nutrition status for magnesium, zinc, calcium, and vitamin D.
Discussion
Findings are inconclusive due to non-standardised trial methodology and a paucity of consideration of inflammatory, lipid and nutritional status. Future trials exploring dietary interventions for chronic wounds in those with diabetes need to investigate inflammatory, lipid and nutritional status for the role of nutrition to be determined.
Chronic wounds are a silent epidemic. Adequate nutrition is essential to optimise nutritional status, glycaemic control, inflammatory and cardiovascular markers, and subsequently wound healing. The aim of this systematic review is to describe dietary interventions impact on nutritional status, and inflammatory and lipid markers in those living with diabetes and chronic wounds.
Methods
Using PRISMA to guide the review, five databases were searched for intervention studies: Medline, Embase, CINAHL, Scopus, Cochrane Library, and clinical trials registries. The Rob-2 and ROBINS tools assessed risk of bias. Inclusion criteria included nutrition intervention studies in people with chronic wounds and diabetes, and reporting of nutritional status, and inflammatory and lipid markers. Results are synthesised narratively.
Results
Out of 10452 texts, twenty-one studies met inclusion criteria. Sixteen were randomised controlled trials and five were non-randomised. Nineteen studies focused on nutrient supplementation alone, one explored nutrient supplementation combined with nutrition education, and one utilised a multidisciplinary team. Approximately half of studies reported inflammatory markers, lipid and nutrient markers. Lipid and inflammatory markers illustrated mixed results, with only one trial noting significance between groups for all inflammatory markers investigated. Seven out of eight studies reported significant improvements in nutrition status for magnesium, zinc, calcium, and vitamin D.
Discussion
Findings are inconclusive due to non-standardised trial methodology and a paucity of consideration of inflammatory, lipid and nutritional status. Future trials exploring dietary interventions for chronic wounds in those with diabetes need to investigate inflammatory, lipid and nutritional status for the role of nutrition to be determined.
| Original language | English |
|---|---|
| Pages (from-to) | S150 |
| Number of pages | 1 |
| Journal | Heart Lung and Circulation |
| Volume | 33 |
| Issue number | Supplement 4 |
| DOIs | |
| Publication status | Published - Aug 2024 |
| Event | Cardiac Society of Australia and New Zealand Annual Scientific Meeting 2024 - Perth Convention and Exhibition Centre, Perth, Australia Duration: 1 Aug 2024 → 4 Aug 2024 Conference number: 72nd https://www.heartlungcirc.org/issue/S1443-9506(24)X0013-X (abstracts published in Journal supplement) https://www.csanzasm.com/ (Conference website) |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
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