Abstract
The epidermal growth factor receptor (EGFR) is a member of the erbB tyrosine kinase family of receptors. For many years it has been believed that receptor activation occurs via a monomer-dimer transition that is associated with a conformational change to activate the kinase. However, little is known about the quaternary state of the receptor at normal levels of expression (
Original language | English |
---|---|
Pages (from-to) | 30392 - 30399 |
Number of pages | 8 |
Journal | Journal of Biological Chemistry |
Volume | 280 |
Issue number | 34 |
Publication status | Published - 2005 |
Externally published | Yes |