Life-long antimicrobial therapy: Where is the evidence?

Jillian Shu Yun Lau, Tony M. Korman, Ian Woolley

Research output: Contribution to journalArticleOtherpeer-review

5 Citations (Scopus)


The decision to prescribe long-term or ‘life-long’ antibiotics in patients requires careful consideration by the treating clinician. While several guidelines exist to help assist in this decision, the long-term consequences are yet to be well studied. In this review, we aim to provide a summary of the available evidence for patient populations where long-term antibiotic therapy is currently recommended in clinical practice. We will also discuss the pitfalls of this approach, including medication adverse effects, economic cost and any possible contribution to the emerging epidemic of microbial resistance.

Original languageEnglish
Pages (from-to)2601-2612
Number of pages12
JournalJournal of Antimicrobial Chemotherapy
Issue number10
Publication statusPublished - 1 Jan 2018

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