LH release and luteal function in post-partum acyclic ewes after the pulsatile administration of LH-RH

P. J. Wright, P. E. Geytenbeek, I. J. Clarke, J. K. Findlay

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The administration of LH-RH in a pulsatile regimen (100 ng i.v./h for 48 h) to acyclic ewes 26-30 days post partum increased plasma LH concentrations, and both the frequency and amplitude of plasma LH pulses. In 12/14 ewes these increases were followed by plasma LH surges similar to the preovulatory surges observed in 10 control cyclic ewes. Subsequent luteal function in the post-partum ewes was deficient. Plasma progesterone was detected in 7/12 post-partum ewes showing plasma LH surges. The concentrations were lower (1.3 ± 0.2 ng/ml) and detected for shorter periods (3-10 days) than in cyclic ewes (2.4 ± 0.2 ng/ml, 12/15 days). In the post-partum ewes the increases in plasma LH concentrations before the LH surge were higher but of shorter duration than in the cyclic ewes. The inadequate luteal function in the post-partum ewes could therefore have been due to inappropriate LH stimulation of the ovary before the LH surge.

Original languageEnglish
Pages (from-to)257-262
Number of pages6
JournalJournal of Reproduction and Fertility
Issue number2
Publication statusPublished - 1 Jan 1983
Externally publishedYes

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