Lewis acid-assisted dirhodium(II)-catalyzed ketone hydroacylation

Tomohiro Yasukawa; Shu Kobayashi

doi:10.1246/cl.160862

Lewis acid-assisted dirhodium(II)-catalyzed ketone hydroacylation

Tomohiro Yasukawa
, Shu Kobayashi

Research output: Contribution to journal › Article › Research › peer-review

7 Citations (Scopus)

Abstract

The combination of a Rh(II) salt and a Lewisacid, Sc(OTf)₃, as a highly active and robust cooperative catalyst system for ketone hydroacylation was developed. The catalyst system showed high turnover numbers (up to ca. 400) even under air, whereas the corresponding Rh(I)/Sc(OTf)₃ system did not work well. The application of the Rh(II)/Sc system was also extended to hydroacylation of olefins and an enantioselective reaction.

Original language	English
Pages (from-to)	98-100
Number of pages	3
Journal	Chemistry Letters
Volume	46
Issue number	1
DOIs	https://doi.org/10.1246/cl.160862
Publication status	Published - 2017
Externally published	Yes

Keywords

Ketone hydroacylation
Lewis acid
Rhodium(II) salt

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10.1246/cl.160862

Cite this

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title = "Lewis acid-assisted dirhodium(II)-catalyzed ketone hydroacylation",

abstract = "The combination of a Rh(II) salt and a Lewisacid, Sc(OTf)3, as a highly active and robust cooperative catalyst system for ketone hydroacylation was developed. The catalyst system showed high turnover numbers (up to ca. 400) even under air, whereas the corresponding Rh(I)/Sc(OTf)3 system did not work well. The application of the Rh(II)/Sc system was also extended to hydroacylation of olefins and an enantioselective reaction.",

keywords = "Ketone hydroacylation, Lewis acid, Rhodium(II) salt",

author = "Tomohiro Yasukawa and Shu Kobayashi",

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volume = "46",

pages = "98--100",

journal = "Chemistry Letters",

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T1 - Lewis acid-assisted dirhodium(II)-catalyzed ketone hydroacylation

AU - Yasukawa, Tomohiro

AU - Kobayashi, Shu

PY - 2017

Y1 - 2017

N2 - The combination of a Rh(II) salt and a Lewisacid, Sc(OTf)3, as a highly active and robust cooperative catalyst system for ketone hydroacylation was developed. The catalyst system showed high turnover numbers (up to ca. 400) even under air, whereas the corresponding Rh(I)/Sc(OTf)3 system did not work well. The application of the Rh(II)/Sc system was also extended to hydroacylation of olefins and an enantioselective reaction.

AB - The combination of a Rh(II) salt and a Lewisacid, Sc(OTf)3, as a highly active and robust cooperative catalyst system for ketone hydroacylation was developed. The catalyst system showed high turnover numbers (up to ca. 400) even under air, whereas the corresponding Rh(I)/Sc(OTf)3 system did not work well. The application of the Rh(II)/Sc system was also extended to hydroacylation of olefins and an enantioselective reaction.

KW - Ketone hydroacylation

KW - Lewis acid

KW - Rhodium(II) salt

UR - https://www.scopus.com/pages/publications/85011552287

U2 - 10.1246/cl.160862

DO - 10.1246/cl.160862

M3 - Article

AN - SCOPUS:85011552287

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VL - 46

SP - 98

EP - 100

JO - Chemistry Letters

JF - Chemistry Letters

IS - 1

ER -

Lewis acid-assisted dirhodium(II)-catalyzed ketone hydroacylation

Abstract

Keywords

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