Lewis acid-assisted dirhodium(II)-catalyzed ketone hydroacylation

Tomohiro Yasukawa, Shu Kobayashi

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Abstract

The combination of a Rh(II) salt and a Lewisacid, Sc(OTf)3, as a highly active and robust cooperative catalyst system for ketone hydroacylation was developed. The catalyst system showed high turnover numbers (up to ca. 400) even under air, whereas the corresponding Rh(I)/Sc(OTf)3 system did not work well. The application of the Rh(II)/Sc system was also extended to hydroacylation of olefins and an enantioselective reaction.

Original languageEnglish
Pages (from-to)98-100
Number of pages3
JournalChemistry Letters
Volume46
Issue number1
DOIs
Publication statusPublished - 2017
Externally publishedYes

Keywords

  • Ketone hydroacylation
  • Lewis acid
  • Rhodium(II) salt

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