Levosimendan infusion improves cardiac output but not blood pressure in a rodent model of severe metoprolol toxicity

Yasmean Kalam, Andis Graudins

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6 Citations (Scopus)

Abstract

Levosimendan (Levo) is an inodilator improving cardiac output (CO) and reducing afterload in heart failure. Previously, we reported that Levo improved CO but not blood pressure (BP) in a rodent model of verapamil poisoning. We theorised that Levo-induced vasodilation should not influence BP to a similar degree in metoprolol poisoning.
Original languageEnglish
Pages (from-to)955 - 963
Number of pages9
JournalHuman and Experimental Toxicology
Volume31
Issue number9
DOIs
Publication statusPublished - 2012

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