Large-Scale Evidence-Based Guideline Development Engaging the International PCOS Community

Marie L. Misso, Eliza C. Tassone, Michael F. Costello, Anuja Dokras, Joop Laven, Lisa J. Moran, Helena J. Teede

Research output: Contribution to journalReview ArticleResearchpeer-review

4 Citations (Scopus)


The evidence-based guideline for the assessment and management of polycystic ovary syndrome (PCOS) integrates the best available evidence with international, multidisciplinary clinical expertise and consumer preferences to provide health professionals, consumers, and policy makers with high-quality, comprehensive guidance about diagnosing and managing PCOS. Here, we outline the rigorous and systematic process, defined a priori and documented to be reproducible, to minimize bias and maintain transparency, in alignment with the Appraisal of Guidelines for Research and Evaluation (AGREE II) criteria and incorporating the Grading of Recommendations Assessment, Development and Evaluation (GRADE) framework that render this PCOS evidence-based guideline credible, trustworthy, reliable, and useable.

Original languageEnglish
Pages (from-to)28-34
Number of pages7
JournalSeminars in Reproductive Medicine
Issue number1
Publication statusPublished - Jan 2018


  • evidence-based guidelines
  • methodology
  • polycystic ovary syndrome

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