Due to the high prevalence of Helicobacter pylori infections in the population, and the cost of treating and difficulty in eradicating the bacteria in all patients, the development of a vaccine has emerged as an alternative in the prevention of H. pylori infections. Tremendous advances have been made over the last four years that permit us, in 1994, to believe that vaccination will be achievable in the future. It has been demonstrated that protection against Helicobacter infections was possible when using oral immunization in an animal model that closely mimics the human infection. Moreover, urease was identified as a protective antigen. It was also recently shown that vaccination might find some application as a therapy for Helicobacter infections.
|Translated title of the contribution||Is vaccination against Helicobacter pylori pure fiction or reality? Who should be vaccinated?|
|Journal||Medecine et Hygiene|
|Publication status||Published - 1 Jan 1994|