Knee osteoarthritis: Current therapeutic strategies

Lionel Schachna, Geoffrey O. Littlejohn

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There is a widespread perception amongst patients with osteoarthritis (OA) of the knee that their condition is a 'wear and tear' problem for which no effective treatment is available. The current framework of therapy is a pyramid approach in which additional therapies are introduced as the disease progresses. However, recent increases in our understanding of the pathogenesis of OA have led to a number of exciting clinical trials of potential disease-modifying anti-OA drugs (DMAODs). Further development of these agents will alter our approach to treatment of this all too common problem.

Original languageEnglish
Pages (from-to)59-65
Number of pages7
JournalCurrent Therapeutics
Issue number1-2
Publication statusPublished - 1 Dec 1999

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