Kingamide A, a new indole alkaloid from the ascidian Leptoclinides kingi

Michelle Liberio; Dhanya Sreedharan; Elizabeth Williams; Yunjiang Feng; Rohan Davis

doi:10.1016/j.tetlet.2011.09.151

Kingamide A, a new indole alkaloid from the ascidian Leptoclinides kingi

Michelle Liberio, Dhanya Sreedharan, Elizabeth Williams, Yunjiang Feng, Rohan Davis

Hudson Institute - Centre for Cancer Research

Research output: Contribution to journal › Article › Research › peer-review

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Abstract

Chemical investigation of the CH2Cl2/MeOH extract from the Australian ascidian Leptoclinides kingi led to the isolation of a new brominated indole alkaloid, kingamide A (1). The planar structure of kingamide A was elucidated following the interpretation of 1D/2D NMR and MS data, and the absolute configuration was determined using Marfey??a??a??s method. This is the first report of a natural product from L. kingi.

Original language	English
Pages (from-to)	6729 - 6731
Number of pages	3
Journal	Tetrahedron Letters
Volume	52
Issue number	50
DOIs	https://doi.org/10.1016/j.tetlet.2011.09.151
Publication status	Published - 2011

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10.1016/j.tetlet.2011.09.151

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title = "Kingamide A, a new indole alkaloid from the ascidian Leptoclinides kingi",

abstract = "Chemical investigation of the CH2Cl2/MeOH extract from the Australian ascidian Leptoclinides kingi led to the isolation of a new brominated indole alkaloid, kingamide A (1). The planar structure of kingamide A was elucidated following the interpretation of 1D/2D NMR and MS data, and the absolute configuration was determined using Marfey??a??a??s method. This is the first report of a natural product from L. kingi.",

author = "Michelle Liberio and Dhanya Sreedharan and Elizabeth Williams and Yunjiang Feng and Rohan Davis",

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doi = "10.1016/j.tetlet.2011.09.151",

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T1 - Kingamide A, a new indole alkaloid from the ascidian Leptoclinides kingi

AU - Liberio, Michelle

AU - Sreedharan, Dhanya

AU - Williams, Elizabeth

AU - Feng, Yunjiang

AU - Davis, Rohan

PY - 2011

Y1 - 2011

N2 - Chemical investigation of the CH2Cl2/MeOH extract from the Australian ascidian Leptoclinides kingi led to the isolation of a new brominated indole alkaloid, kingamide A (1). The planar structure of kingamide A was elucidated following the interpretation of 1D/2D NMR and MS data, and the absolute configuration was determined using Marfey??a??a??s method. This is the first report of a natural product from L. kingi.

AB - Chemical investigation of the CH2Cl2/MeOH extract from the Australian ascidian Leptoclinides kingi led to the isolation of a new brominated indole alkaloid, kingamide A (1). The planar structure of kingamide A was elucidated following the interpretation of 1D/2D NMR and MS data, and the absolute configuration was determined using Marfey??a??a??s method. This is the first report of a natural product from L. kingi.

UR - http://www.sciencedirect.com/science/article/pii/S0040403911017060

U2 - 10.1016/j.tetlet.2011.09.151

DO - 10.1016/j.tetlet.2011.09.151

M3 - Article

SN - 0040-4039

VL - 52

SP - 6729

EP - 6731

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 50

ER -

Kingamide A, a new indole alkaloid from the ascidian Leptoclinides kingi

Abstract

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