TY - JOUR
T1 - Kinetically Controlled Dendritic Mesoporous Silica Nanoparticles
T2 - From Dahlia- to Pomegranate-like Structures by Micelle Filling
AU - Wang, Yue
AU - Song, Hao
AU - Yang, Yannan
AU - Liu, Yang
AU - Tang, Jie
AU - Yu, Chengzhong
N1 - Funding Information:
The authors acknowledge financial support from the Australian Research Council, the Queensland Government, the Australian National Fabrication Facility, and the Australian Microscopy and Microanalysis Research Facility at the Centre for Microscopy and Microanalysis and University of Queensland.
Publisher Copyright:
© 2018 American Chemical Society.
PY - 2018/8/28
Y1 - 2018/8/28
N2 - A unique dynamic structural transition from large-pore dendritic mesoporous silica nanoparticles (DMSNs) with a dahlia-like morphology to pomegranate-like mesoporous silica nanoparticles with small mesopores is reported. The structural evolution is accompanied by gradually filling the preformed dendritic large pores with silica-coated micelles, providing a series of DMSNs with kinetically controlled dual mesoporosity. The heterogeneous porous structure of DMSNs demonstrates advantages in the co-loading of two positively charged drug molecules, showing promising potential in cellular delivery applications.
AB - A unique dynamic structural transition from large-pore dendritic mesoporous silica nanoparticles (DMSNs) with a dahlia-like morphology to pomegranate-like mesoporous silica nanoparticles with small mesopores is reported. The structural evolution is accompanied by gradually filling the preformed dendritic large pores with silica-coated micelles, providing a series of DMSNs with kinetically controlled dual mesoporosity. The heterogeneous porous structure of DMSNs demonstrates advantages in the co-loading of two positively charged drug molecules, showing promising potential in cellular delivery applications.
UR - http://www.scopus.com/inward/record.url?scp=85052630415&partnerID=8YFLogxK
U2 - 10.1021/acs.chemmater.8b02712
DO - 10.1021/acs.chemmater.8b02712
M3 - Article
AN - SCOPUS:85052630415
SN - 0897-4756
VL - 30
SP - 5770
EP - 5776
JO - Chemistry of Materials
JF - Chemistry of Materials
IS - 16
ER -