Kinetic and system bias as drivers of metabotropic glutamate receptor 5 allosteric modulator pharmacology

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• Finished

  G Protein-Coupled Receptor Context-Specific Biased Agonism to Treat Ischaemic Heart Disease

  May, L. (Primary Chief Investigator (PCI))

  National Heart Foundation of Australia

  1/01/18 → 13/09/22

  Project: Research

• Exploring metabotropic glutamate receptor 5 bias, allostery and heteromers

  Gregory, K. (Primary Chief Investigator (PCI))

  1/07/17 → 30/12/21

  Project: Research

• Understanding bias and allostery at the calcium sensing receptor

  Leach, K. (Primary Chief Investigator (PCI))

  ARC - Australian Research Council, Monash University

  1/01/17 → 22/07/22

  Project: Research

• Biased allosteric modulators of metabotropic glutamate receptors: novel therapeutic targets for CNS disorders

  Gregory, K. (Primary Chief Investigator (PCI))

  NHMRC - National Health and Medical Research Council (Australia)

  1/01/15 → 31/12/18

  Project: Research

• The Janus face of G Protein-Coupled Receptors: Implications for Disease Mechanisms and Opportunities for Drug Discovery

  Sexton, P. (Primary Chief Investigator (PCI)), Bunnett, N. (Chief Investigator (CI)), Christopoulos, A. (Chief Investigator (CI)) & Summers, R. (Chief Investigator (CI))

  NHMRC - National Health and Medical Research Council (Australia)

  1/01/14 → 31/12/18

  Project: Research

• Positive allosteric modulation of metabotropic glutamate receptor 5; a novel approach for the treatment of schizophrenia and cognitive disorders

  Gregory, K. (Primary Chief Investigator (PCI))

  NHMRC - National Health and Medical Research Council (Australia)

  1/01/11 → 31/12/15

  Project: Research

• NHMRC Research Fellowship

  Christopoulos, A. (Primary Chief Investigator (PCI))

  NHMRC - National Health and Medical Research Council (Australia)

  1/01/05 → 31/12/20

  Project: Research