Kawasaki disease in Australia, 1993-95

Jennifer A. Royle, Katrina Williams, Elizabeth Elliott, Gary Sholler, Terry Nolan, Roger Allen, David Isaacs

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Abstract

Aim - To describe the epidemiology, management, and rate of cardiac sequelae of Kawasaki disease in Australia. Design - Cases were notified to the Australian Paediatric Surveillance Unit, an active national surveillance scheme, from May 1993 to June 1995. Results - 139 cases of Kawasaki disease were confirmed. In 1994, the annual incidence was 3.7/100 000 children < 5 years old. Sixteen children were not admitted to hospital. Coronary artery abnormalities were reported in 35 (25%) children. Two patients were diagnosed at postmortem examination. Sixty six per cent of patients were diagnosed within 10 days of onset and 81% of these received intravenous gammaglobulin within 10 days. Forty five of the notified children did not fulfil the study criteria because of streptococcal infection or insufficient clinical criteria. One child with streptococcal infection had coronary artery dilatation. Conclusion - Diagnosis of Kawasaki disease was delayed beyond 10 days in one third of patients, and almost 20% of children who could have received gamma globulin within 10 days did not. The distinction between Kawasaki disease, streptococcal infection, and other possible diagnoses is problematic in some children.

Original languageEnglish
Pages (from-to)33-39
Number of pages7
JournalArchives of Disease in Childhood
Volume78
Issue number1
DOIs
Publication statusPublished - 1 Jan 1998
Externally publishedYes

Keywords

  • Classification
  • Epidemiology
  • Kawasaki disease

Cite this

Royle, J. A., Williams, K., Elliott, E., Sholler, G., Nolan, T., Allen, R., & Isaacs, D. (1998). Kawasaki disease in Australia, 1993-95. Archives of Disease in Childhood, 78(1), 33-39. https://doi.org/10.1136/adc.78.1.33