Abstract
Studies of subclinical vascular changes post-Kawasaki disease indicate that, in general, individuals with a history of coronary artery aneurysms have increased carotid intima-media thickness, evidence of endothelial dysfunction, and increased arterial stiffness, possibly indicative of heightened cardiovascular risk. The results are less consistent for low-risk groups. Conclusion Until data are available from larger prospective studies, it is prudent to advise families of individuals with a history of Kawasaki disease to minimise traditional modifiable cardiovascular risk factors.
Original language | English |
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Pages (from-to) | 752-761 |
Number of pages | 10 |
Journal | Acta Paediatrica |
Volume | 105 |
Issue number | 7 |
DOIs | |
Publication status | Published - 1 Jul 2016 |
Keywords
- Carotid intima-media thickness
- Endothelial function
- Kawasaki disease
- Mucocutaneous lymph node syndrome
- Vascular stiffness