Isothermal titration calorimetry studies on the binding of DNA bases and PNA base monomers to gold nanoparticles

A. Gourishankar, Sourabh Shukla, Krishna N. Ganesh, Murali Sastry

Research output: Contribution to journalArticleOtherpeer-review

117 Citations (Scopus)

Abstract

An isothermal titration calorimetric (ITC) investigation of the interaction of DNA bases and PNA base monomers with gold nanoparticles is described revealing a binding sequence in the order C > G > A > T. Direct measurement of the strength of interaction of ligands with nanogold by ITC has important implications in surface modification strategies for biomedical, catalysis, and nanoarchitecture applications.

Original languageEnglish
Pages (from-to)13186-13187
Number of pages2
JournalJournal of the American Chemical Society
Volume126
Issue number41
DOIs
Publication statusPublished - 20 Oct 2004
Externally publishedYes

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