Ischemic stroke risk and passive exposure to spouses' cigarette smoking. Melbourne Stroke Risk Factor Study (MERFS) Group.

Roger X. You, Amanda G. Thrift, John J. McNeil, Stephen M. Davis, Geoffrey A. Donnan

Research output: Contribution to journalArticleResearchpeer-review

84 Citations (Scopus)


Objectives. This study investigated the association between ischemic stroke risk and passive exposure to cigarette smoking. Methods. Risk factors among 452 hospitalized cases of first-episode ischemic stroke were compared with 452 age- and sex-matched 'neighborhood' controls. Results. The risk of stroke was twice as high for subjects whose spouses smoked as for those whose spouses did not smoke (95% confidence interval = 1.3, 3.1), after adjustment for the subject's own smoking, heart disease, hypertension, diabetes, and education level. These results were confirmed when analysis was limited to those who never smoked. Conclusions. These findings provide evidence that spousal smoking may be a significant risk factor for ischemic stroke.

Original languageEnglish
Pages (from-to)572-575
Number of pages4
JournalAmerican Journal of Public Health
Issue number4
Publication statusPublished - Apr 1999

Cite this