Ischaemic stroke and transient ischaemic attack on anticoagulants: outcomes in the era of direct oral anticoagulants

Michael Valente, Shelton Leung, Philip Wu, Danielle H. Oh, Hyuen Tran, Philip M.C. Choi

Research output: Contribution to journalArticleResearchpeer-review

Abstract

Clinical and imaging characteristics of patients receiving direct oral anticoagulants presenting with transient ischaemic attack or stroke are lacking. A retrospective review of all patients who presented to a high-volume primary stroke centre with acute stroke symptoms while prescribed an oral anticoagulant between January 2012 and June 2017. Clinical, radiological characteristics and functional outcomes were examined. Anticoagulated patients diagnosed with stroke or transient ischaemic attack shared similar disease and outcome characteristics irrespective of anticoagulants used. One-third of warfarin patients with sub-therapeutic international normalised ratios were treated with thrombolytics but no direct oral anticoagulants level was performed in any of the patients, with only one treated by intravenous thrombolysis.

Original languageEnglish
Pages (from-to)110-113
Number of pages4
JournalInternal Medicine Journal
Volume50
Issue number1
DOIs
Publication statusPublished - Jan 2020

Keywords

  • anticoagulant
  • direct oral anticoagulant
  • stroke
  • transient ischaemic attack
  • warfarin

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