Isavuconazole (Basilea Pharmaceutica, Basel, Switzerland) is a broad-spectrum prodrug triazole with efficacy against a range of medically important fungi including Aspergillus spp. and the Mucorales. Isavuconazonium (BAL-8557) is the water-soluble prodrug of isavuconazole (BAL-4815), which is the active moiety. The conversion to isavuconazole is rapid and complete. Isavuconazole is the newest member of the triazole class of antifungals and has an important role in the treatment of life-threatening invasive fungal diseases (IFDs).
|Title of host publication||Kucers the Use of Antibiotics|
|Subtitle of host publication||A Clinical Review of Antibacterial, Antifungal, Antiparasitic, and Antiviral Drugs|
|Editors||M. Lindsay Grayson|
|Place of Publication||Boca Raton FL USA|
|Number of pages||12|
|Publication status||Published - 2 Oct 2017|