Is target dose of beta-blocker more important than achieved heart rate or heart rate change in patients with systolic chronic heart failure?

Pornwalee Porapakkham, Pramote Porapakkham, Henry Krum

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Abstract

Beta-blockers (BBs) are mandatory therapy for patients with systolic chronic heart failure (CHF). However, it is uncertain whether target dose of these agents is more important than the achievement of target heart rate (HR) in maximizing the benefits of these agents. To test this, we obtained ECG absolute HR from patients with systolic CHF, together with consecutive left ventricular ejection fraction (EF) measures at least 3 months apart.
Original languageEnglish
Pages (from-to)93 - 100
Number of pages8
JournalCardiovascular Therapeutics
Volume28
Issue number2
DOIs
Publication statusPublished - 2010

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