Iridium-mediated borylation of benzylic C-H bonds by borohydride

Christina Y. Tang; William Smith; Amber L. Thompson; Dragoslav Vidovic; Simon Aldridge

doi:10.1002/anie.201006320

Iridium-mediated borylation of benzylic C-H bonds by borohydride

Christina Y. Tang
, William Smith
, Amber L. Thompson
, Dragoslav Vidovic
, Simon Aldridge

Research output: Contribution to journal › Article › Research › peer-review

50 Citations (Scopus)

Abstract

Simple source: An intramolecular iridium-mediated C-H borylation proceeds through transfer of a BH₃ fragment from borohydride to a benzylic carbon center (see scheme; coe=cyclooctene). Simple and inexpensive LiBH ₄ is thus utilized as the boron source in C-H to C-B conversion.

Original language	English
Pages (from-to)	1359-1362
Number of pages	4
Journal	Angewandte Chemie - International Edition
Volume	50
Issue number	6
DOIs	https://doi.org/10.1002/anie.201006320
Publication status	Published - 7 Feb 2011
Externally published	Yes

Keywords

boron
borylation
C-H activation
iridium
N-heterocyclic ligands

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10.1002/anie.201006320

Cite this

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title = "Iridium-mediated borylation of benzylic C-H bonds by borohydride",

abstract = "Simple source: An intramolecular iridium-mediated C-H borylation proceeds through transfer of a BH3 fragment from borohydride to a benzylic carbon center (see scheme; coe=cyclooctene). Simple and inexpensive LiBH 4 is thus utilized as the boron source in C-H to C-B conversion.",

keywords = "boron, borylation, C-H activation, iridium, N-heterocyclic ligands",

author = "Tang, \{Christina Y.\} and William Smith and Thompson, \{Amber L.\} and Dragoslav Vidovic and Simon Aldridge",

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AU - Tang, Christina Y.

AU - Smith, William

AU - Thompson, Amber L.

AU - Vidovic, Dragoslav

AU - Aldridge, Simon

PY - 2011/2/7

Y1 - 2011/2/7

N2 - Simple source: An intramolecular iridium-mediated C-H borylation proceeds through transfer of a BH3 fragment from borohydride to a benzylic carbon center (see scheme; coe=cyclooctene). Simple and inexpensive LiBH 4 is thus utilized as the boron source in C-H to C-B conversion.

AB - Simple source: An intramolecular iridium-mediated C-H borylation proceeds through transfer of a BH3 fragment from borohydride to a benzylic carbon center (see scheme; coe=cyclooctene). Simple and inexpensive LiBH 4 is thus utilized as the boron source in C-H to C-B conversion.

KW - boron

KW - borylation

KW - C-H activation

KW - iridium

KW - N-heterocyclic ligands

UR - https://www.scopus.com/pages/publications/79551654732

U2 - 10.1002/anie.201006320

DO - 10.1002/anie.201006320

M3 - Article

AN - SCOPUS:79551654732

SN - 1433-7851

VL - 50

SP - 1359

EP - 1362

JO - Angewandte Chemie - International Edition

JF - Angewandte Chemie - International Edition

IS - 6

ER -

Iridium-mediated borylation of benzylic C-H bonds by borohydride

Abstract

Keywords

Access to Document

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