Iridium-mediated borylation of benzylic C-H bonds by borohydride

Christina Y. Tang; William Smith; Amber L. Thompson; Dragoslav Vidovic; Simon Aldridge

doi:10.1002/anie.201006320

Iridium-mediated borylation of benzylic C-H bonds by borohydride

Christina Y. Tang, William Smith, Amber L. Thompson, Dragoslav Vidovic, Simon Aldridge

Research output: Contribution to journal › Article › Research › peer-review

45 Citations (Scopus)

Abstract

Simple source: An intramolecular iridium-mediated C-H borylation proceeds through transfer of a BH₃ fragment from borohydride to a benzylic carbon center (see scheme; coe=cyclooctene). Simple and inexpensive LiBH ₄ is thus utilized as the boron source in C-H to C-B conversion.

Original language	English
Pages (from-to)	1359-1362
Number of pages	4
Journal	Angewandte Chemie - International Edition
Volume	50
Issue number	6
DOIs	https://doi.org/10.1002/anie.201006320
Publication status	Published - 7 Feb 2011
Externally published	Yes

Keywords

boron
borylation
C-H activation
iridium
N-heterocyclic ligands

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10.1002/anie.201006320

Cite this

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abstract = "Simple source: An intramolecular iridium-mediated C-H borylation proceeds through transfer of a BH3 fragment from borohydride to a benzylic carbon center (see scheme; coe=cyclooctene). Simple and inexpensive LiBH 4 is thus utilized as the boron source in C-H to C-B conversion.",

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AU - Tang, Christina Y.

AU - Smith, William

AU - Thompson, Amber L.

AU - Vidovic, Dragoslav

AU - Aldridge, Simon

PY - 2011/2/7

Y1 - 2011/2/7

N2 - Simple source: An intramolecular iridium-mediated C-H borylation proceeds through transfer of a BH3 fragment from borohydride to a benzylic carbon center (see scheme; coe=cyclooctene). Simple and inexpensive LiBH 4 is thus utilized as the boron source in C-H to C-B conversion.

AB - Simple source: An intramolecular iridium-mediated C-H borylation proceeds through transfer of a BH3 fragment from borohydride to a benzylic carbon center (see scheme; coe=cyclooctene). Simple and inexpensive LiBH 4 is thus utilized as the boron source in C-H to C-B conversion.

KW - boron

KW - borylation

KW - C-H activation

KW - iridium

KW - N-heterocyclic ligands

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M3 - Article

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JO - Angewandte Chemie - International Edition

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Iridium-mediated borylation of benzylic C-H bonds by borohydride

Abstract

Keywords

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