Iridium-mediated borylation of benzylic C-H bonds by borohydride

Christina Y. Tang, William Smith, Amber L. Thompson, Dragoslav Vidovic, Simon Aldridge

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43 Citations (Scopus)

Abstract

Simple source: An intramolecular iridium-mediated C-H borylation proceeds through transfer of a BH3 fragment from borohydride to a benzylic carbon center (see scheme; coe=cyclooctene). Simple and inexpensive LiBH 4 is thus utilized as the boron source in C-H to C-B conversion.

Original languageEnglish
Pages (from-to)1359-1362
Number of pages4
JournalAngewandte Chemie - International Edition
Volume50
Issue number6
DOIs
Publication statusPublished - 7 Feb 2011
Externally publishedYes

Keywords

  • boron
  • borylation
  • C-H activation
  • iridium
  • N-heterocyclic ligands

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