Investigator-initiated randomized clinical trials in infectious diseases: the BALANCE experience

Nick Daneman; Asgar H. Rishu; Ruxandra Pinto; Yaseen M. Arabi; Deborah J. Cook; Richard Hall; John Muscedere; Rachael Parke; Steven Reynolds; Benjamin Rogers; Yahya Shehabi; Robert A. Fowler; on behalf of the BALANCE Investigators for the Canadian Critical Care Trials Group (CCCTG), Association of Medical Microbiology and Infectious Disease Canada Clinical Research Network (AMMI CRN), Australian and New Zealand Intensive Care Society (ANZICS) Clinical Trials Group, the Australasian Society of Infectious Diseases (ASID) Clinical Research Network

doi:10.1016/j.cmi.2025.02.033

Investigator-initiated randomized clinical trials in infectious diseases: the BALANCE experience

Nick Daneman, Asgar H. Rishu, Ruxandra Pinto, Yaseen M. Arabi, Deborah J. Cook, Richard Hall, John Muscedere, Rachael Parke, Steven Reynolds, Benjamin Rogers, Yahya Shehabi, Robert A. Fowler, on behalf of the BALANCE Investigators for the Canadian Critical Care Trials Group (CCCTG), Association of Medical Microbiology and Infectious Disease Canada Clinical Research Network (AMMI CRN), Australian and New Zealand Intensive Care Society (ANZICS) Clinical Trials Group, the Australasian Society of Infectious Diseases (ASID) Clinical Research Network

Research output: Contribution to journal › Comment / Debate › Other › peer-review

Original language	English
Number of pages	4
Journal	Clinical Microbiology and Infection
DOIs	https://doi.org/10.1016/j.cmi.2025.02.033
Publication status	Accepted/In press - 2025

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1016/j.cmi.2025.02.033

Cite this

Daneman, N., Rishu, A. H., Pinto, R., Arabi, Y. M., Cook, D. J., Hall, R., Muscedere, J., Parke, R., Reynolds, S., Rogers, B., Shehabi, Y., Fowler, R. A., & on behalf of the BALANCE Investigators for the Canadian Critical Care Trials Group (CCCTG), Association of Medical Microbiology and Infectious Disease Canada Clinical Research Network (AMMI CRN), Australian and New Zealand Intensive Care Society (ANZICS) Clinical Trials Group, the Australasian Society of Infectious Diseases (ASID) Clinical Research Network (Accepted/In press). Investigator-initiated randomized clinical trials in infectious diseases: the BALANCE experience. Clinical Microbiology and Infection. https://doi.org/10.1016/j.cmi.2025.02.033

@article{10b33b6bcc09478c839c673157031c81,

title = "Investigator-initiated randomized clinical trials in infectious diseases: the BALANCE experience",

author = "Nick Daneman and Rishu, {Asgar H.} and Ruxandra Pinto and Arabi, {Yaseen M.} and Cook, {Deborah J.} and Richard Hall and John Muscedere and Rachael Parke and Steven Reynolds and Benjamin Rogers and Yahya Shehabi and Fowler, {Robert A.} and {on behalf of the BALANCE Investigators for the Canadian Critical Care Trials Group (CCCTG), Association of Medical Microbiology and Infectious Disease Canada Clinical Research Network (AMMI CRN), Australian and New Zealand Intensive Care Society (ANZICS) Clinical Trials Group, the Australasian Society of Infectious Diseases (ASID) Clinical Research Network}",

year = "2025",

doi = "10.1016/j.cmi.2025.02.033",

language = "English",

journal = "Clinical Microbiology and Infection",

issn = "1198-743X",

publisher = "Elsevier",

}

Daneman, N, Rishu, AH, Pinto, R, Arabi, YM, Cook, DJ, Hall, R, Muscedere, J, Parke, R, Reynolds, S, Rogers, B , Shehabi, Y, Fowler, RA & on behalf of the BALANCE Investigators for the Canadian Critical Care Trials Group (CCCTG), Association of Medical Microbiology and Infectious Disease Canada Clinical Research Network (AMMI CRN), Australian and New Zealand Intensive Care Society (ANZICS) Clinical Trials Group, the Australasian Society of Infectious Diseases (ASID) Clinical Research Network 2025, 'Investigator-initiated randomized clinical trials in infectious diseases: the BALANCE experience', Clinical Microbiology and Infection. https://doi.org/10.1016/j.cmi.2025.02.033

TY - JOUR

T1 - Investigator-initiated randomized clinical trials in infectious diseases

T2 - the BALANCE experience

AU - Daneman, Nick

AU - Rishu, Asgar H.

AU - Pinto, Ruxandra

AU - Arabi, Yaseen M.

AU - Cook, Deborah J.

AU - Hall, Richard

AU - Muscedere, John

AU - Parke, Rachael

AU - Reynolds, Steven

AU - Rogers, Benjamin

AU - Shehabi, Yahya

AU - Fowler, Robert A.

AU - on behalf of the BALANCE Investigators for the Canadian Critical Care Trials Group (CCCTG), Association of Medical Microbiology and Infectious Disease Canada Clinical Research Network (AMMI CRN), Australian and New Zealand Intensive Care Society (ANZICS)

PY - 2025

Y1 - 2025

UR - http://www.scopus.com/inward/record.url?scp=105000611504&partnerID=8YFLogxK

U2 - 10.1016/j.cmi.2025.02.033

DO - 10.1016/j.cmi.2025.02.033

M3 - Comment / Debate

C2 - 40024529

AN - SCOPUS:105000611504

SN - 1198-743X

JO - Clinical Microbiology and Infection

JF - Clinical Microbiology and Infection

ER -

Investigator-initiated randomized clinical trials in infectious diseases: the BALANCE experience

UN SDGs

Access to Document

Other files and links

Cite this