"Inverted" tako-tsubo cardiomyopathy due to exogenous catecholamines

Ashwin Subramaniam, Jennifer Cooke, David Ernest

Research output: Contribution to journalArticleOther

19 Citations (Scopus)

Abstract

Inverted tako-tsubo cardiomyopathy (TTC) is a variation of stress cardiomyopathy. It features transient myocardial dysfunction characterised by a typical contractile abnormality consisting of extensive left ventricular circumferential dyskinesia or akinesia with a hyperkinetic apex. Endogenous catecholamine surges are believed to be the mediators of this potentially life-threatening condition. We describe a patient who received an inadvertent bolus of noradrenaline and developed significant haemodynamic instability associated with electrocardiographic and cardiac biomarkers indicative of diffuse myocardial injury and echocardiography findings of an inverted TTC. The patient made a full recovery. Our case highlights that a reversible inverted TTC may result from an exogenous catecholamine surge.
Original languageEnglish
Pages (from-to)104 - 108
Number of pages5
JournalCritical Care and Resuscitation
Volume12
Issue number2
Publication statusPublished - 2010

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