The concept of drugs behaving as either stimulants of receptor systems (agonists) or inhibitors (antagonists) has been the conceptual basis for drug action for many years. Research based on this concept has produced most of the drugs we presently have available to us. This article outlines a new concept which has emerged from recent fundamental research, that of inverse agonism. Only time will tell if new and useful drugs emerge as a result of exploiting this.
|Number of pages||4|
|Journal||Australian Journal of Pharmacy|
|Publication status||Published - 1 Aug 1996|