Intravascular Ultrasound Studies of Plaque Progression and Regression: Impact of Lipid-Modifying Therapies

Daisuke Shishikura, Satoshi Honda, Jordan Andrews, Stephen J. Nicholls

Research output: Contribution to journalReview ArticleOtherpeer-review


Application of serial intravascular ultrasound imaging within the coronary arteries enables characterization of the factors associated with progression of atherosclerotic plaque. Integration into clinical trials has enabled determination of the impact of medical therapies on coronary disease. These trials have provided important insights into the effects of lipid-modifying agents currently used in clinical practice and of experimental agents at early stages of clinical development. The results of these trials are reviewed.

Original languageEnglish
Pages (from-to)329-334
Number of pages6
JournalCardiology Clinics
Issue number2
Publication statusPublished - 1 May 2018
Externally publishedYes


  • Atherosclerosis
  • Clinical trials
  • Intravascular ultrasound
  • Lipids

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