Intrapulmonary shunting in primary pulmonary hypertension: An observation in two patients treated with epoprostenol sodium

Pablo F. Castro; Robert C. Bourge; David C. McGiffin; Raymond L. Benza; Pohoey Fan; Nanette B. Pinkard; Michael D. McGoon

doi:10.1378/chest.114.1.334

Intrapulmonary shunting in primary pulmonary hypertension: An observation in two patients treated with epoprostenol sodium

Pablo F. Castro, Robert C. Bourge, David C. McGiffin, Raymond L. Benza, Pohoey Fan, Nanette B. Pinkard, Michael D. McGoon

Research output: Contribution to journal › Article › Research › peer-review

22 Citations (Scopus)

Abstract

Continuous intravenous infusion of epoprostenol sodium in selected patients with primary pulmonary hypertension improves symptoms and survival. This report describes two patients with primary pulmonary hypertension treated with epoprostenol in whom intrapulmonary shunting and severe hypoxemia occurred, Intrapulmonary shunting was confirmed by contrast echocardiography showing delayed appearance of bubbles in the left cardiac chambers after peripheral venous injection of agitated saline solution.

Original language	English
Pages (from-to)	334-336
Number of pages	3
Journal	Chest
Volume	114
Issue number	1
DOIs	https://doi.org/10.1378/chest.114.1.334
Publication status	Published - 1 Jan 1998
Externally published	Yes

Keywords

Contrast echocardiography
Epoprostenol
Hypoxemia
Intrapulmonary shunting
Primary pulmonary hypertension

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10.1378/chest.114.1.334

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abstract = "Continuous intravenous infusion of epoprostenol sodium in selected patients with primary pulmonary hypertension improves symptoms and survival. This report describes two patients with primary pulmonary hypertension treated with epoprostenol in whom intrapulmonary shunting and severe hypoxemia occurred, Intrapulmonary shunting was confirmed by contrast echocardiography showing delayed appearance of bubbles in the left cardiac chambers after peripheral venous injection of agitated saline solution.",

keywords = "Contrast echocardiography, Epoprostenol, Hypoxemia, Intrapulmonary shunting, Primary pulmonary hypertension",

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AU - Benza, Raymond L.

AU - Fan, Pohoey

AU - Pinkard, Nanette B.

AU - McGoon, Michael D.

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AB - Continuous intravenous infusion of epoprostenol sodium in selected patients with primary pulmonary hypertension improves symptoms and survival. This report describes two patients with primary pulmonary hypertension treated with epoprostenol in whom intrapulmonary shunting and severe hypoxemia occurred, Intrapulmonary shunting was confirmed by contrast echocardiography showing delayed appearance of bubbles in the left cardiac chambers after peripheral venous injection of agitated saline solution.

KW - Contrast echocardiography

KW - Epoprostenol

KW - Hypoxemia

KW - Intrapulmonary shunting

KW - Primary pulmonary hypertension

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Intrapulmonary shunting in primary pulmonary hypertension: An observation in two patients treated with epoprostenol sodium

Abstract

Keywords

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