TY - JOUR
T1 - Intramedullary spinal cord metastasis from thyroid carcinoma
T2 - Case report and a systematic pooled analysis of the literature
AU - O'Neill, Anthea H.
AU - Phung, Teik Beng
AU - Lai, Leon T.
N1 - Publisher Copyright:
© 2017 Elsevier Ltd
PY - 2018/3
Y1 - 2018/3
N2 - Intramedullary spinal cord metastasis (ISCM) is rare and occurs most commonly in the setting of advanced malignancy. The optimal management pathways are not well defined and treatment outcomes from contemporary therapies remain variable. We report a case of a 49-year-old woman with known primary papillary thyroid carcinoma, who presented with rapidly progressive clinical features of Brown-Sequard syndrome. A detailed pooled analysis of the literature was conducted to characterise the clinical and demographic features, management options, and expected survival outcomes for cases of ISCM. We secondarily performed a subgroup analysis on the incidence, clinical and management characteristics of thyroid carcinoma ISCM.
AB - Intramedullary spinal cord metastasis (ISCM) is rare and occurs most commonly in the setting of advanced malignancy. The optimal management pathways are not well defined and treatment outcomes from contemporary therapies remain variable. We report a case of a 49-year-old woman with known primary papillary thyroid carcinoma, who presented with rapidly progressive clinical features of Brown-Sequard syndrome. A detailed pooled analysis of the literature was conducted to characterise the clinical and demographic features, management options, and expected survival outcomes for cases of ISCM. We secondarily performed a subgroup analysis on the incidence, clinical and management characteristics of thyroid carcinoma ISCM.
KW - Intramedullary metastasis
KW - Papillary thyroid carcinoma
KW - Spinal cord tumour
UR - http://www.scopus.com/inward/record.url?scp=85039035895&partnerID=8YFLogxK
U2 - 10.1016/j.jocn.2017.12.001
DO - 10.1016/j.jocn.2017.12.001
M3 - Review Article
C2 - 29248379
AN - SCOPUS:85039035895
SN - 0967-5868
VL - 49
SP - 7
EP - 15
JO - Journal of Clinical Neuroscience
JF - Journal of Clinical Neuroscience
ER -