Intramedullary spinal cord metastasis from thyroid carcinoma: Case report and a systematic pooled analysis of the literature

Anthea H. O'Neill, Teik Beng Phung, Leon T. Lai

Research output: Contribution to journalReview ArticleOtherpeer-review

12 Citations (Scopus)

Abstract

Intramedullary spinal cord metastasis (ISCM) is rare and occurs most commonly in the setting of advanced malignancy. The optimal management pathways are not well defined and treatment outcomes from contemporary therapies remain variable. We report a case of a 49-year-old woman with known primary papillary thyroid carcinoma, who presented with rapidly progressive clinical features of Brown-Sequard syndrome. A detailed pooled analysis of the literature was conducted to characterise the clinical and demographic features, management options, and expected survival outcomes for cases of ISCM. We secondarily performed a subgroup analysis on the incidence, clinical and management characteristics of thyroid carcinoma ISCM.

Original languageEnglish
Pages (from-to)7-15
Number of pages9
JournalJournal of Clinical Neuroscience
Volume49
DOIs
Publication statusPublished - Mar 2018

Keywords

  • Intramedullary metastasis
  • Papillary thyroid carcinoma
  • Spinal cord tumour

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