Interventions to prevent bloodstream infections associated with central venous access devices: Priorities for an adaptive platform trial

Claire M. Rickard; Andrew J. Stewardson; Sally M. Havers; Niccolo Buetti; Kevan R. Polkinghorne; Aleece MacPhail; Zoe McQuilten; Benjamin Lazarus; Karina R. Charles; Jessica A. Schults; on behalf of the IVCare Trial Study Group

doi:10.1016/j.ajic.2025.06.003

Interventions to prevent bloodstream infections associated with central venous access devices: Priorities for an adaptive platform trial

Claire M. Rickard
, Andrew J. Stewardson
, Sally M. Havers
, Niccolo Buetti
, Kevan R. Polkinghorne
, Aleece MacPhail
, Zoe McQuilten
, Benjamin Lazarus
, Karina R. Charles
, Jessica A. Schults
, on behalf of the IVCare Trial Study Group

Research output: Contribution to journal › Article › Research › peer-review

2 Citations (Scopus)

Abstract

Health care-associated bloodstream infections are serious complications of central venous access devices. Numerous preventative interventions exist, but without high-level evidence. The IVCare adaptive platform trial will provide multiple answers for infection prevention. A prioritization study with infection preventionists using the Society for Healthcare Epidemiology of America central line-associated bloodstream infection prevention framework identified priorities for IVCare intervention testing as: vascular access teams, education/competency for central venous access device insertion/postinsertion care, sutureless securement, connector type and decontamination method.

Original language	English
Pages (from-to)	1004-1007
Number of pages	4
Journal	American Journal of Infection Control
Volume	53
Issue number	9
DOIs	https://doi.org/10.1016/j.ajic.2025.06.003
Publication status	Published - Sept 2025

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Catheter-related infections
Catheterization
Cross infection*/Prevention and control
Infection control
Infection control practitioners
Priorization studies

Access to Document

10.1016/j.ajic.2025.06.003Licence: CC BY

Cite this

Rickard, C. M., Stewardson, A. J., Havers, S. M., Buetti, N., Polkinghorne, K. R., MacPhail, A., McQuilten, Z., Lazarus, B., Charles, K. R., Schults, J. A., & on behalf of the IVCare Trial Study Group (2025). Interventions to prevent bloodstream infections associated with central venous access devices: Priorities for an adaptive platform trial. American Journal of Infection Control, 53(9), 1004-1007. https://doi.org/10.1016/j.ajic.2025.06.003

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title = "Interventions to prevent bloodstream infections associated with central venous access devices: Priorities for an adaptive platform trial",

abstract = "Health care-associated bloodstream infections are serious complications of central venous access devices. Numerous preventative interventions exist, but without high-level evidence. The IVCare adaptive platform trial will provide multiple answers for infection prevention. A prioritization study with infection preventionists using the Society for Healthcare Epidemiology of America central line-associated bloodstream infection prevention framework identified priorities for IVCare intervention testing as: vascular access teams, education/competency for central venous access device insertion/postinsertion care, sutureless securement, connector type and decontamination method.",

keywords = "Catheter-related infections, Catheterization, Cross infection*/Prevention and control, Infection control, Infection control practitioners, Priorization studies",

author = "Rickard, \{Claire M.\} and Stewardson, \{Andrew J.\} and Havers, \{Sally M.\} and Niccolo Buetti and Polkinghorne, \{Kevan R.\} and Aleece MacPhail and Zoe McQuilten and Benjamin Lazarus and Charles, \{Karina R.\} and Schults, \{Jessica A.\} and \{on behalf of the IVCare Trial Study Group\}",

note = "Publisher Copyright: {\textcopyright} 2025 The Authors",

year = "2025",

month = sep,

doi = "10.1016/j.ajic.2025.06.003",

language = "English",

volume = "53",

pages = "1004--1007",

journal = "American Journal of Infection Control",

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Rickard, CM, Stewardson, AJ, Havers, SM, Buetti, N, Polkinghorne, KR , MacPhail, A , McQuilten, Z, Lazarus, B, Charles, KR, Schults, JA & on behalf of the IVCare Trial Study Group 2025, 'Interventions to prevent bloodstream infections associated with central venous access devices: Priorities for an adaptive platform trial', American Journal of Infection Control, vol. 53, no. 9, pp. 1004-1007. https://doi.org/10.1016/j.ajic.2025.06.003

TY - JOUR

T1 - Interventions to prevent bloodstream infections associated with central venous access devices

T2 - Priorities for an adaptive platform trial

AU - Rickard, Claire M.

AU - Stewardson, Andrew J.

AU - Havers, Sally M.

AU - Buetti, Niccolo

AU - Polkinghorne, Kevan R.

AU - MacPhail, Aleece

AU - McQuilten, Zoe

AU - Lazarus, Benjamin

AU - Charles, Karina R.

AU - Schults, Jessica A.

AU - on behalf of the IVCare Trial Study Group

PY - 2025/9

Y1 - 2025/9

N2 - Health care-associated bloodstream infections are serious complications of central venous access devices. Numerous preventative interventions exist, but without high-level evidence. The IVCare adaptive platform trial will provide multiple answers for infection prevention. A prioritization study with infection preventionists using the Society for Healthcare Epidemiology of America central line-associated bloodstream infection prevention framework identified priorities for IVCare intervention testing as: vascular access teams, education/competency for central venous access device insertion/postinsertion care, sutureless securement, connector type and decontamination method.

AB - Health care-associated bloodstream infections are serious complications of central venous access devices. Numerous preventative interventions exist, but without high-level evidence. The IVCare adaptive platform trial will provide multiple answers for infection prevention. A prioritization study with infection preventionists using the Society for Healthcare Epidemiology of America central line-associated bloodstream infection prevention framework identified priorities for IVCare intervention testing as: vascular access teams, education/competency for central venous access device insertion/postinsertion care, sutureless securement, connector type and decontamination method.

KW - Catheter-related infections

KW - Catheterization

KW - Cross infection/Prevention and control

KW - Infection control

KW - Infection control practitioners

KW - Priorization studies

UR - https://www.scopus.com/pages/publications/105009692253

U2 - 10.1016/j.ajic.2025.06.003

DO - 10.1016/j.ajic.2025.06.003

M3 - Article

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AN - SCOPUS:105009692253

SN - 0196-6553

VL - 53

SP - 1004

EP - 1007

JO - American Journal of Infection Control

JF - American Journal of Infection Control

IS - 9

ER -

Interventions to prevent bloodstream infections associated with central venous access devices: Priorities for an adaptive platform trial

Abstract

UN SDGs

Keywords

Access to Document

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